1. Explain how a high-nurturing mother rat shapes her pup's epigenome, and what that
pup's response to stress will be.
In the hippocampus of the brain, one of its jobs is to relieve stress. Depending how much the pup was nurtured will affect how much of the GR protein is produced; the more the better. During the fight or flight The brain produces the hormone cortisol which is put into the blood stream. When connected/bind to the GR protein, which will cause the cell to send out calming signals. The more nurture the rat has from its mother, the quicker the pup will recover from the stress.
2. In rats, does licking by the mother activate, or deactivate her pup's GR gene?
The mother's licking will activate the pup's GR gene.
3. Explain how cortisol and the GR protein work together in the brain to relax a rat pup.
You may draw a diagram.
Depending how much the pup was nurtured will affect how much of the GR protein is produced; the more the better. The more of the GP protein is created, the quicker the pup will be able to release stress. During the fight or flight The brain produces the hormone cortisol which is put into the blood stream. When connected/bind to the GR protein, which will cause the cell to send out calming signals. The more nurture the rat has from its mother, the quicker the pup will recover from the stress.
4. The rat nurturing example shows us how parental behavior can shape the behavior of
their offspring on a biochemical level. Relate this to humans and think about the personal
and social implications. Record your thoughts.
The love that is shown to a child can be the grooming of the rat. The more love, affection, and praise, the child grows up on will make them have a more friendly personality. The amount of affection showed can also affect the person's personality.
UTRITION & THE EPIGENOME
1. Explain how the food we eat affects gene expression.
"Familiar nutrients like folic acid, B vitamins and SAM-e (S-Adenosyl methionine, a popular over-the-counter supplement) are key components of this methyl-making pathway. Diets high in these methyl-donating nutrients can rapidly alter gene expression, especially during early development when the epigenome is first being established."
2. Can the diets of parents affect their offspring's epigenome?
Yes. When a mother consumes food, she is "feeding two." The food that the mother eats when you are in the womb is extremely important. What your mother eats during pregnancy will affect you throughout your entire. The father of the child has a part of the epigenome. How much the grandfather ate between the ages of nine and twelve can affect the lifespan on his grandchildren. "Shortage of food for the grandfather was associated with extended lifespan of his grandchildren. Food abundance, on the other hand, was associated with a greatly shortened lifespan of the grandchildren." I read this article that was talking about the link from the mother to the child. The foods that the mother eats are more likely to attract the child in the later life, with the tastes/flavors and smells. The article was also talking about the influence of alcohol. Mothers, consuming alcohol, can have children may be more attracted to alcohol because the developing fetus 'expects' that whatever comes from the mother must be safe." The more healthier the mother eats, the more attracted the child is to healthier.
EPIGENETICS & THE HUMAN BRAIN
1. How does Dietary methyl influence gene expression?
Basically, The Dietary Methyl influence gene is expression when you have a certain amount of methyl that your body will retain from the nutrients in your food. This food needs to be able to make you healthy. You have a significantly higher chance of becoming obese if you have a methyl-deficient diet.
2. Why do Toxins affect gene methylation?
The toxins affect the gene methylation by ruining your health. Different chemicals can have different affects. Take the chemical BPA for instance. BPA can cause endocrine problems like obesity, stunted growth, and birth defects.